Corrections or additions?
This article by Barbara Fox was prepared for the May 29, 2002 edition of U.S. 1 Newspaper. All rights reserved.
The search for gene-based pain therapies at Purdue Pharma’s
new 115,000 square foot facility is being enhanced by a wireless network.
No matter where the researchers are working — at the lab bench
or in the cubicles — they can connect their laptops to the genome
sequences on the Internet and the company’s bioinformatics databases.
Tage Honore, head of Purdue Pharma’s new R&D group, says that though
his organization is entrepreneurial, it has deeper pockets than its
cohorts, so it has enough money for such "extras" as the wireless
network. "In our soul, we are like a biotech company but we have
a `big pharma’ economic structure," says Honore.
Honore, 51, was educated in Denmark, is married, and has two school-aged
children. Known for the discovery of the Ampa excitatory neuroreceptor,
Honore most recently directed research at Novartis in Switzerland.
When he came to head the R&D efforts at Purdue Pharma in October 2000,
60 people had already been hired. At 115,000 square feet in Cranbury,
he is hiring genomics, informatics, and proteomic scientists to raise
the head count from 110 to 140.
Commitment to computer technology is integral to Purdue Pharma, a
subsidiary of Purdue Frederick, a privately owned company funded in
large part by the Sackler family. The fact that, early in the history
of the Web, the company plucked a plum website name — pharma.com
— would bear this out. "You can guess the family applied for
that name very early in the Internet story," says Honore.
The ownes are committed to developing new medicine for pain. "We
put two new potential drug candidates in the pipeline in the first
year, and they have very competitive profiles. One is a broad spectrum
sodium channel blocker for pain, and the other is a neuro steroid
for insomnia," says Honore.
Corporate Center, Cranbury 08512. Tage Honore, vice president of discovery
research. 609-409-5123; fax, 609-409-5799. Home page: www.purduepharma.com
Seven centimeters is a long way for your scalpel to
cut if you are cutting into someone’s brain to find a tumor. You hope
you know precisely where that tumor is. As it turns out, the ability
to conjure up three-dimensional pictures of someone’s anatomy can
be the difference between a good surgeon and a great surgeon. A great
surgeon "sees" what is below any surface in a three-dimensional
Until now, surgeons have had to look at a scan of a tumor on a light
screen, put it together with their minds’ eye views of an anatomical
model, and then try to imagine where that tumor is. But a new Siemens
technology can essentially render the patient transparent to the surgeon.
This "in-situ visualization," a kind of augmented reality
(AR), lets the surgeon see a tumor in three-dimensional space from
different angles, says Frank Sauer, a project manager at Siemens Corporate
Research on College Road. He received his undergraduate degree in
Stuttgart and has a PhD in optical information technology from the
University of Erlangen, and has been working at Siemens for 10 years.
"The ability to look inside the patient and see the tumor in three-dimensional
space from different angles helps the surgeon determine the best route
to the tumor," says Sauer. His prototype — discussed 10 years
ago but made possible now by faster computers — uses a head-mounted
display with three miniature cameras. Two of them take a stereoscopic
(3D) view of the surgical site, and the third is used for viewpoint
tracking, so that no matter which way the head is angled, the user
sees the correct view. "We want the surgeon to have direct access
to this information and make it available in context with the patient’s
body," says Sauer. A metal "halo" helps to keep everything
Pre-clinical tests on "phantom" objects have been performed,
and results are encouraging. Clinical testing could begin by the end
Road, Forrestal Center, Princeton 08540. Norbert Gaus, CEO. 609-734-6500;
fax, 609-734-6565. Www.scr.siemens.com
Princeton 08542. 609-921-0888; fax, 609-921-6442.
J. Kerney Kuser II has expanded to 1,000 square feet with a move from
1 Palmer Square to 230 Nassau Stret. A graduate of Kenyon College
and the Seton Hall School of Law, he specializes in real estate, trusts
and estates, and corporate law. His great grandfather had owned the
6, Suite 615, Princeton 08540. Joseph (Mandella, director. 609-799-8856.
Home page: www.home-care.net
To honor the founder of this 20-year-old company, Jean Griswold of
Erdenheim, Pennsylvania, the nursing service provider has changed
its name from Special Care to Griswold Special Care. It has more than
70 offices in 12 states, and there is a Middlesex County office at
732-745-7788. The company offers caregivers for a wide range of conditions
on an hourly, overnight, or live-in basis.
site supervisor. 908-965-0056 or 800-672-7676; fax, 908-965-1596.
Home page: www.bostoncoach.com
Boston Coach, a limousine firm, has closed its office at Research
Park (19 Wall Street) and is planning to move it to Bridgewater, but
in the meantime is operating out of the New York area headquarters
in Elizabeth. Three years ago it had started a satellite branch here
with a fleet of 25 Volvos.
of Homasote Company on Lower Ferry Road.
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