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Published in U.S. 1 Newspaper on May 17, 2000. All rights reserved.
Princeton’s R&D Community Part II
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Drug Development
Takeda America Research and Development Center Inc.,
104 Carnegie Center, Princeton 08540; 609-452-1113; fax, 609-452-1218.
www.takeda-america.com. Founded 1997. Mikihiko Obayashi PhD,
president. Staff size: 35. Square feet: 12,000.
Pharmaceutical research and development of new prescription
medication from IND filing stage through FDA approval. FDA approval
has been received for Actos, an insulin sensitizer for patients with
Type 2 (non insulin-dependent) diabetes.
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Gene Sequencing
DNX Transgenic Sciences, 5 Cedar Brook Drive,
Cranbury 08512; 609-860-0806; fax, 609-860-8515. www.dnxsciences.com.
Stock symbol: CRLS. Founded 1985. Mark E. Swanson, vice president
transgenic sciences. Rick Coffee. Staff size: 53. Square feet: 12,000.
Research and development of therapeutic products and biological
testing services based on transgenic mice and rats, using techniques
of gene addition, gene targeting, homologous recombination and microinjection
techniques for the study of gene function and to identify and validate
new genetic targets for pharmaceutical development. It has produced
more than 8,000 transgenic mice and rats from more than 1,450 gene
constructs.
Interlink Biotechnologies LLC, 215 Commons Way,
Montgomery Commons, Princeton 08540; 609-252-0446; fax, 609-252-9416.
www.interlinkbiotech.com. Founded 1991. Ramon L. Garcia, president.
Staff size: 5. Square feet: 2,000.
Biotechnology assessment, planning and transfer, also
microbial products and services with InterLink Microbials division.
InterLink provides microbial natural product leads and genes for discovery
research in the pharmaceutical, agricultural, food, feed, and chemical
industries. It also conducts research in antimicrobial peptides and
genetic engineering of plants — particularly forestry and fruit
species. Technology transfer, assessment, and strategic planning services
are also offered.
Orchid BioSciences Inc., 303A College Road East,
Box 2197, Princeton 08540-2197; 609-750-2200; fax, 609-750-2250. www.orchid.com.
Stock symbol: ORCH. Founded 1995. Dale R. Pfost Ph.D, chairman, president
and CEO. Staff size: 200.
Production services and technologies of single nucleotide
polymorphism (SNP) scoring and genetic diversity analysis. This newly
public company provides products, services, and technologies for single
nucleotide polymorphism (SNP) scoring and genetic diversity analyses.
It develops proprietary SNP analysis technologies (SNP-IT), it markets
SNPstream instruments and SNPware consumables that rapidly generate
highly accurate SNP information at a significantly lower cost than
conventional systems. The SNP-IT can be used by both small-scale laboratories
and large commercial facilities. This adaptability also enables Orchid
to partner with industry leaders to make SNP-IT products available
on a wide variety of instrument platforms. Alto, through its Clinical
Genetics Network (CGN), Orchid seeks to identify proprietary medical
applications of SNPs.
When Orchid made its $6 million initial public offering
on Friday, May 5, it sold out at $8 a share — lower than the expected
$11 to $13 — but it shot up to almost $18, closed at $11 on the
first day, and is now hovering around $12. Sarnoff Corporation, beaming
proudly at the first of its spinoffs to go public, owns 5.9 percent
of the company.
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Imaging
Bracco Research USA Inc., 305 College Road East,
Princeton 08540; 609-514-2409; fax, 609-514-2446. Founded 1994. Michael F. Tweedle, president and CEO. Staff
size: 45. Square feet: 25,580.
Diagnostic imaging agents and targeted drug delivery research,
associated with Bracco SPA of Milan.
Medical Accessories Inc., 92 Youngs Road, Hamilton
08619; 609-890-8304; fax, 609-890-0638.
Founded 1976. Janis G. Ziedonis, technical director.
Ultrasound technology, transducers and accessories used
in fetal monitoring.
Nycomed Amersham Imaging in the Americas, 101
Carnegie Center, Princeton 08540; 609-514-6000; fax, 609-514-6572.
www.us-nai.com. Stock symbol: NYE. Daniel L. Peters, president.
Staff size: 300. Square feet: 115,000.
Headquarters of R&D, manufacturing, and marketing firm
operating in the western hemisphere, specialty in medical diagnostics
and radiotherapy products. New imaging agents and oncology therapies
help doctors help patients live longer, healthier lives.
Sirius Corporation, 104 Interchange Plaza, Suite
202, Cranbury 08512; 609-409-4449; fax, 609-409-4450. www.siriuscorp.com.
Founded 1994. Tom Carulli, CEO. Staff size: 15. Square feet: 4,700.
Medical imaging software for sending images electronically
through medical networks.
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Laboratory Services
Bohlin Instruments Inc., 11 Harts Lane, Suite
I, East Brunswick 08816; 732-254-7742; fax, 732-254-1577. www.bohlinusa.com.
Founded 1983. Sean Race, president. Staff size: 9.
Instrumentation and measurement of flow properties (rheometers
& viscometers) for such industries as pharmaceutical, paints & coatings,
asphalt, cosmetics, food, and polymers. In the asphalt industry it
dominates the binder equipment business, and it is developing new
products in other areas.
Corporate Environmental Services Inc., 23 Route
31 North, Suite B24, Pennington 08534; 609-730-0040; fax, 609-730-1711.
Founded 1989. Frank Jankoski, president and CEO. Staff size: 5. Square
feet: 1,000.
Environmental consulting on hazardous materials, waste
management, air permits, wastewater, and OSHA, specialist to chemical,
pharmaceutical, biotech, and R&D businesses.
E-Beam Services Inc., 32 Melrich Road, Cranbury
08512-3511; 609-655-7460; fax, 609-655-3052. www.ebeamservices.com.
Founded 1986. Bill Crilley, director of quality assurance. Staff size:
35.
Electron beam irradiation for terminal sterilization and
bio burden reduction of medical products. Also material modification,
enhancement, crosslinking, chain scission, and rheology control for
plastics, wife, cable, tubing, sheet products, and semiconductors.
Evans East, 104 Windsor Center, Suite 101, East
Windsor 08520; 609-371-4800; fax, 609-371-5666. www.evanseast.com.
Founded 1987. William L. Harrington, executive director. Staff size:
22. Square feet: 15,000.
Analytical service company specializing in the characterization
of surfaces, thin films, and high purity materials. Surfaces play
a critical role in industrial technology — to optimize production,
boost yield, reduce failure, improve quality, and speed new product
development. These techniques can be used for such applications as
semiconductors, polymers, biological materials, ceramics and glasses,
metals, lubricants and magnetic media.
Synthon Corp., 7 Deer Park Drive, Monmouth Junction
08852; 732-274-0037; fax, 732-274-0501. www.synthoncorp.com.
Founded 1995. Scott E. Coleridge, president & CEO. Staff size: 25.
A fine chemicals and custom synthesis company that can
produce high purity chiral intermediates for the pharmaceutical and
biotechnology industries. It can simplify the process of developing
batches of chiral (mirror image) molecules to meet FDA requirements.
It has shown it can do this in drugs for cholesterol reduction, central
nervous system disorders (anti-depressants), antibiotics, muscle relaxants,
and anti-virals.
Tyger Scientific Inc., 324 Stokes Avenue, Ewing
08638; 609-434-0144; fax, 609-434-0143. www.tygersci.com. Founded
1995. Adam Yuan, president. Staff size: 7. Square feet: 2,300.
Custom synthesis and contract research for chemicals and
biochemicals.
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Services
CP Packaging, 1075 Cranbury South River Road,
Suite 5, Jamesburg 08831; 609-655-4880; fax, 609-655-5718. www.cppackaging.com.
Founded 1972. Rick O’Connell, vice president/general manager. Staff
size: 50. Square feet: 22,000.
Unit dose packaging for the pharmaceutical industry —
tubes, contract packaging, and machinery.
Clinical Trial Services, Drug Accountability and
Disposal Division, 11 Princess Road, Suite A and B, Lawrenceville
08648-2319; 609-844-1025; fax, 609-844-1024. www.cts-usa.com.
Founded 1987. Jack Yarin, director. Staff size: 9. Square feet: 20,000.
Packaging, distribution, accountability, and disposal
of new and experimental drugs used in clinical research trials.
ClinPhone, 29 Emmons Drive, Building C-40, Princeton
08540; 609-734-4800; fax, 609-734-0502. www.clinphone.com. Founded
1993. Howard Goldberg, vice president. Staff size: 5. Square feet:
2,100.
New interactive voice response systems and online/offline
Internet-based systems for clinical trial can reduce time-consuming
manual data collection and processing (U.S. 1, June 23, 1999). The
automated technology is available in a 24×7 environment via toll-free
numbers in numerous countries and languages. The flexible system allows
studies to begin with low clinical supply levels, permits mid-study
changes, and enables a large number of participants to record and
review information simultaneously and remotely in real time. Real
time inventory control saves money. Automatic study closure means
no over-enrollment and tight control of expiration dates with minimum
inventory.
Integrated Communications Corp., 989 Lenox Drive,
Building One, Suite 300, Lawrenceville 08648; 609-406-9600; fax, 609-406-9046.
Founded 1985. Larry J. Iaquinto, president. Staff size: 101. Square
feet: 30,000.
Worldwide headquarters for full service medical advertising
agency for pharmaceutical and health imaging marketplace.
Newton Resource Group, 2425 Pennington Road,
Pennington 08534; 609-818-0025; fax, 609-818-0045. www.nrg-i.com.
Founded 1991. Debra Newton, president. Staff size: 25.
Digital media for the healthcare and pharmaceutical industries,
specializing in web-based solutions — websites, intranets, extranets,
web-based training, and CD-ROMs, including Web-based learning solutions
for pharmaceutical manufacturers’ sales training departments (U.S.
1, April 12).
Pharmaceutical Profiles, 116 Village Boulevard,
Suite 200, Princeton 08540; 609-951-2205; fax, 609-951-2232. www.pharmprofiles.com.
David Friend.
Phase I clinical studies using gamma scintigraphy, also
site specific drug delivery tools to study regional drug absorption.
PharmaPros, 2633 Main Street, Lawrenceville 08648;
609-912-1100; fax, 609-912-1120. www.pharmapros.com. Peg Regan,
president.
Key business solutions to the healthcare industry —
pharmaceutical companies, contract research organizations, medical
device companies, and biotechnology companies, (U.S. 1, August 18,
1999). Just launched: DataVal, a robust library of PL/SQL programs
that support the design, development, and maintenance of data validation
programs for clinical data management that comes with software, consulting,
training, and ongoing technical support.
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Electronic
Linearizer Technology Inc., 3 Nami Lane, Unit
9C, Hamilton 08619; 609-584-8424; fax, 609-631-0177. www.lintech.com.
Founded 1991. Allen Katz, president. Staff size: 26. Square feet:
7,500.
TWTA and Klystron amplifier linearizers for satellite
groundstations, also a manufacturing facility. Known for its TWTA
and Klystron amplifier linearizers used in satellite ground stations
worldwide, this firm develops innovative ways to solve the problem
of non-linearity (in other words, correct the distortions) in communications
systems. This year, for the terrestrial amplifier market, it launched
an input adaptive linearizer that automatically adjusts to changing
signal characteristics.
ML Energia Inc., Schalks Crossing Road, IRL Building,
Box 470, Princeton 08542; 609-799-7970; fax, 609-799-0312.
Founded 1982. Moshe Lavid, president. Staff size: 9. Square
feet: 5,000.
Research on the interaction between photons and chemical
species and on the "judicious deposition of spectrally selective
energy into specifically targeted absorbing molecules." Also an
optical moisture (water vapor) sensor based on fluorescent film, liquid
oxygen/methanol sprays for maneuvering space vehicles, reductive photo-dechlorination
of solvents, photo-thermal destruction of sites contaminated with
hazardous solvents (converting Freons and other ozone-depleting substances
into environmentally benign and commercially valuable products), and
photo-thermal destruction of air pollutants in power plants.
Millennium Cell LLC, 1 Industrial Way West, Eatontown
07724; 732-542-4000; fax, 732-542-4010. www.millenniumcell.com.
Founded 1998. Steven Amendola, vice president, research. Staff size:
13. Square feet: 9,700.
Development of an aqueous battery to be used in electric
vehicles plus on-demand hydrogen generation, and an extremely safe
generator for producing controlled amounts of hydrogen gas from water-based
solutions. The hydrogen gas, rapidly formed on-demand by the generator,
can either be converted through fuel cells to produce electricity
and pure water, or burned directly as a clean nonpolluting fuel in
internal combustion engines.
Triveni Digital Inc. (formerly LGERCA), 40 Washington
Road, Princeton Junction 08550; 609-716-3500; fax, 609-716-3503. www.3veni.com.
Founded 1997. Mark Simpson, president. Staff size: 25. Square feet:
12,000.
Digital television software, systems and solutions, PC-DTV
systems, data broadcast receivers and solutions, digital TV standards.
The name has changed from LGERCA to Triveni Digital Inc.
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General
Listings below were cut for space and did not run in the print edition.
American Cyanamid Agricultural Products Research
Division, Quakerbridge Road, Box 400, Princeton 08543-0400; 609-716-2000;
fax, 609-275-5234. www.cyanamid.com. Stock symbol: AHP. Founded
1907. Mark W. Atwood, president, global agricultural products research
division. Staff size: 700.
Global headquarters for agricultural and biotechnology
research, a subsidiary of American Home Products Corporation.
Bristol-Myers Squibb Company, Route 206 and Provinceline
Road, Box 4000, Princeton 08543-4000; 609-252-4000.
Stock symbol: BMY. Founded 1970. Richard J. Lane, president,
worldwide medicines group. Staff size: 2,000.
Worldwide medicines group headquarters, research and development,
Also Pharmaceutical Research Institute headquarters (Peter S. Ringrose,
president).
Comprehensive Medical Group, 32 Nassau Street,
Second Floor, Princeton 08542; 609-924-1001; fax, 609-924-4442.
Founded 1994. James Clingham, CEO. Staff size: 4. Square
feet: 1,700.
Data collection, analysis, and management to link individuals,
organizations, sponsors, and product/service providers, also Galaxis
USA. The health and wellness company privately markets a mobile diagnostic
kiosk and Internet site for corporations, unions, and organizations.
TRI/Princeton: Textile Research Institute, 601
Prospect Avenue, Box 625, Princeton 08542-0625; 609-924-3150; fax,
609-683-7836. www.triprinceton.com. Founded 1930. Gail R. Eaton,
president. Staff size: 40.
Research and technical services for industry, government,
and academia in the United States and abroad focusing on physical
and engineering sciences of fibers, engineering plastics (composites),
films, hair, and hair care products, absorbent products, textiles and
porous materials (from angstroms to millimeters).
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