Dr. Jeffrey Apter

Alzheimer’s disease is really the plague of our modern century. With the aging of the baby boomer generation, incidences of the disease are expected to double in America by the year 2050.

Princeton Medical Institute was the first and only site in New Jersey chosen to be part of the Global Alzheimer Platform. The goal of the GAP is to get a drug approved by 2025. PMI is working to help find a way to fight Alzheimer’s disease. The best way to do that is through the advances of science, and clinical trials are the only way to get medications approved. The Global Alzheimer’s Platform promotes advancing Alzheimer’s disease medications and awareness from the laboratory all the way through clinical research trials. PMI also conducts trials for depression, schizophrenia, episodic cluster headaches, and fatty livers.

Major contributing factors to Alzheimer’s disease are amyloids that build up in the brain and destroy connections between nerve cells. This is the only aspect of the disease that current drug treatments target.

Princeton Medical Institute is conducting trials of two new medications that target other causes. Research has shown that there may be an association between gingivitis and Alzheimer’s disease.

We’re now moving beyond amyloids and are pleased to announce two unique studies for patients with Alzheimer’s disease. We are working with Cortexyme, which has a new medication targeting gingivitis as the cause of the disease.

The other very exciting program we’re working with is with Oryzon Pharmaceuticals. This offers an epigenetic approach, which is also different. It’s a membrane stabilizer that causes stabilization of the disease.

Participants in these studies will see a board certified doctor on a regular basis, get full blood work, physical exams, and EKG, CAT, MRI, and PET scans. All treatment is free and insurance is not needed. Transportation can be provided by Lyft. Stipends will be paid for your time and travel. The trials last about a year, and they will follow up with patients afterwards. They also stay in contact with the patient’s regular doctor. All test results can be provided to their regular doctor.

Patients don’t already have a diagnosis to participate in these studies. Free testing is provided for those who are concerned that they may be developing the disease. If you are concerned about yourself or a loved one, and your memory is not functioning as well as it used to — for example you are having difficulty remembering things or performing tasks you used to perform easily — this is an indication that you should come in for testing.

Participation in these trials is crucial in the fight against Alzheimer’s disease. We need your help.

Princeton Medical Institute, 256 Bunn Drive, Suite 6, Princeton. www.princetonmedicalinstitute.org or 609-921-6050.

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