Some of the greatest challenges to the treatment of depression and anxiety disorders are the long waits of weeks to months for effect and the burden of side effects such as weight gain or sleepiness. Despite many gains in the past several decades in our understanding of depression and anxiety, many continue to feel frustrated by partially effective and difficult-to-tolerate treatment options.

Ketamine is an anesthetic medicine that was developed more than 50 years ago and has been safely used since that time for both children and adults. More recently, research has demonstrated that Ketamine may be administered intravenously in doses far below those used for surgery to provide rapid relief from symptoms of depression and anxiety.

Whereas most of the currently available treatments take weeks to months to improve symptoms, Ketamine can provide significant improvement of symptoms of major depression, depression associated with bipolar disorder, post-traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), and certain pain disorders within hours.

This is an off-label use of Ketamine, meaning that the FDA has not approved this medication for this use. However, it is FDA-approved for other uses, its safety and effectiveness has been demonstrated in multiple research studies, and off-label prescribing is a common and necessary practice in all fields of medicine.

Dr. Steven Levine pioneered the clinical use of ketamine in 2011, and today, Ketamine Treatment Centers has treated more than 1,200 patients and provided 10,000 infusions.

Dr. Levine received his psychiatry training in Manhattan at New York-Presbyterian/Weill Cornell Medical Center and Memorial Sloan Kettering Cancer Center. His undergraduate degree is from the Johns Hopkins University and M.D. degree from Tulane University. He is an internationally recognized expert in the use of ketamine and speaks and publishes widely.

KTC now welcomes psychiatrist Dr. Patricia Carneval. Dr. Carneval is a board-certified psychiatrist practicing in the Princeton area for the past 21 years. She has experience in hospital settings, academic settings, and in private practice. She specializes in psychotherapy and psychopharmacology for depression, anxiety, PTSD, and life transitions. She graduated from the University of Pittsburgh with a BS in biology, and later with her MD degree. She did residencies at the Pennsylvania Hospital in Philadelphia, first in general surgery then in psychiatry.

Further information is available by visiting the practice website at or calling to arrange a consultation at 888-566-8774.

Ketamine Treatment Centers of Princeton, 800 Bunn Drive, Suite 304, Princeton. 888-566-8774.

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